About 3 results found for searched term "Brigatinib C" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43427 | Brigatinib C | PROTAC Linker |
| Brigatinib C is a linker, as a part of PROTAC Linker to target HJM-561. | ||
| M1720 | AP26113 (Brigatinib) | ALK |
| Brigatinib | ||
| AP26113 (Brigatinib) is a highly potent ALK inhibitor with IC50 of 0.6 nM. | ||
| M29525 | SIAIS164018 | PROTAC |
| SIAIS164018 is a PROTAC-based ALK and EGFR degrader, which is designed from Brigatinib, with IC50 value of 2.5 nM and 6.6 nM for ALK and ALK G1202R, respectively. SIAIS164018 strongly inhibits cancer cells migration and invasion, causes G1 cell cycle arrest and induces apoptosis. SIAIS164018 exhibits better property than Brigatinib. | ||
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